Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CHOLBAM | Mirum Pharmaceuticals | N-205750 RX | 2015-03-17 | 2 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
cholbam | New Drug Application | 2025-05-09 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
zellweger syndrome | Orphanet_912 | D015211 | E71.510 |
Code | Description |
---|---|
J0591 | Injection, deoxycholic acid, 1 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Biliary liver cirrhosis | D008105 | — | K74.3 | 3 | 5 | 8 | 3 | 5 | 22 |
Liver diseases | D008107 | EFO_0001421 | K70-K77 | 3 | 9 | 2 | 3 | 5 | 21 |
Cholangitis | D002761 | HP_0030151 | K83.0 | 2 | 3 | 5 | 2 | 5 | 15 |
Fibrosis | D005355 | — | — | 3 | 2 | 4 | 1 | 6 | 15 |
Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | 3 | 1 | 4 | 1 | 4 | 12 |
Non-alcoholic fatty liver disease | D065626 | EFO_0003095 | K75.81 | — | 5 | — | 3 | 4 | 12 |
Fatty liver | D005234 | EFO_0003934 | — | — | 5 | — | 2 | 4 | 11 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 2 | 2 | 2 | 2 | 2 | 9 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | — | 3 | 4 | 2 | 1 | 8 |
Gallstones | D042882 | EFO_0004210 | — | — | — | 2 | 4 | 1 | 7 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cholestasis | D002779 | — | K83.1 | — | 6 | 7 | — | 4 | 14 |
Healthy volunteers/patients | — | — | — | 6 | — | 3 | — | 1 | 10 |
Intrahepatic cholestasis | D002780 | — | — | — | 4 | 4 | — | 1 | 7 |
Colorectal neoplasms | D015179 | — | — | 1 | 4 | 2 | — | — | 5 |
Cerebrotendinous xanthomatosis | D019294 | — | — | 1 | 1 | 1 | — | 2 | 5 |
Xanthomatosis | D014973 | — | — | 1 | 1 | 1 | — | 2 | 5 |
Hepatitis a | D006506 | EFO_0007305 | B15 | — | 2 | 1 | — | 1 | 4 |
Malnutrition | D044342 | EFO_0008572 | E40-E46 | 2 | 1 | 1 | — | 1 | 4 |
Pregnancy complications | D011248 | — | — | — | 1 | 2 | — | 1 | 3 |
Glucose intolerance | D018149 | HP_0000833 | R73.03 | 1 | 1 | 1 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Alcoholic fatty liver | D005235 | — | K70.0 | — | 1 | — | — | 2 | 3 |
Gastrointestinal diseases | D005767 | — | — | 1 | 3 | — | — | — | 3 |
Digestive system diseases | D004066 | EFO_0000405 | K92.9 | 1 | 3 | — | — | — | 3 |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | 1 | — | — | 1 | 2 |
Lipodystrophy | D008060 | — | E88.1 | — | 2 | — | — | — | 2 |
Lipoma | D008067 | — | D17.9 | 1 | 1 | — | — | — | 2 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | 2 | — | — | — | 2 |
Arthritis | D001168 | EFO_0005856 | M05-M14 | — | 2 | — | — | — | 2 |
Biliary tract diseases | D001660 | EFO_0009534 | K83.9 | 1 | 2 | — | — | — | 2 |
Barrett esophagus | D001471 | EFO_0000280 | K22.7 | — | 1 | — | — | 1 | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neurofibromatosis 1 | D009456 | — | Q85.01 | 4 | — | — | — | — | 4 |
Neurofibromatoses | D017253 | — | Q85.00 | 4 | — | — | — | — | 4 |
Neurofibroma | D009455 | EFO_0000622 | — | 4 | — | — | — | — | 4 |
Hyperlipidemias | D006949 | EFO_0003774 | E78.5 | 1 | — | — | — | 1 | 2 |
Central nervous system neoplasms | D016543 | — | — | 1 | — | — | — | 1 | 2 |
Aging | D000375 | GO_0007568 | R41.81 | 1 | — | — | — | 1 | 2 |
Clostridium infections | D003015 | EFO_1000874 | A05.2 | 1 | — | — | — | 1 | 2 |
Colonic neoplasms | D003110 | — | C18 | 1 | — | — | — | — | 1 |
Rectal neoplasms | D012004 | — | — | 1 | — | — | — | — | 1 |
Echolocation | D004455 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Fontan procedure | D018729 | — | — | — | — | — | — | 2 | 2 |
Infections | D007239 | EFO_0000544 | — | — | — | — | — | 2 | 2 |
Communicable diseases | D003141 | — | — | — | — | — | — | 2 | 2 |
Dermatitis | D003872 | — | L30.9 | — | — | — | — | 1 | 1 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | — | — | — | — | 1 | 1 |
Sarcoma | D012509 | — | — | — | — | — | — | 1 | 1 |
Germ cell and embryonal neoplasms | D009373 | — | — | — | — | — | — | 1 | 1 |
Medulloblastoma | D008527 | — | — | — | — | — | — | 1 | 1 |
Retinoblastoma | D012175 | — | — | — | — | — | — | 1 | 1 |
Rhabdoid tumor | D018335 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Cholic acid |
INN | — |
Description | Cholic acid is a bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12. It has a role as a human metabolite and a mouse metabolite. It is a bile acid, a C24-steroid, a 3alpha-hydroxy steroid, a 7alpha-hydroxy steroid, a 12alpha-hydroxy steroid and a trihydroxy-5beta-cholanic acid. It is a conjugate acid of a cholate. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@H]3[C@H](C[C@H](O)[C@@]21C)[C@@]1(C)CC[C@@H](O)C[C@H]1C[C@H]3O |
PDB | — |
CAS-ID | 81-25-4 |
RxCUI | — |
ChEMBL ID | CHEMBL205596 |
ChEBI ID | 16359 |
PubChem CID | 221493 |
DrugBank | DB02659 |
UNII ID | — |