Tradename | Company | Number | Date | Products |
---|---|---|---|---|
CHOLBAM | Mirum Pharmaceuticals | N-205750 RX | 2015-03-17 | 2 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
cholbam | New Drug Application | 2023-03-13 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
zellweger syndrome | Orphanet_912 | D015211 | E71.510 |
Code | Description |
---|---|
J0591 | Injection, deoxycholic acid, 1 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Inborn errors steroid metabolism | D043202 | — | — | — | — | 1 | — | — | 1 |
Cholestasis | D002779 | — | K83.1 | — | — | 1 | — | — | 1 |
Peroxisomal disorders | D018901 | Orphanet_44 | E71.5 | — | — | 1 | — | — | 1 |
Zellweger syndrome | D015211 | Orphanet_912 | E71.510 | — | — | 1 | — | — | 1 |
Infantile refsum disease | D052919 | Orphanet_772 | G60.1 | — | — | 1 | — | — | 1 |
Adrenoleukodystrophy | D000326 | Orphanet_43 | E71.52 | — | — | 1 | — | — | 1 |
Refsum disease | D012035 | Orphanet_773 | G60.1 | — | — | 1 | — | — | 1 |
Drug common name | Cholic acid |
INN | — |
Description | Cholic acid is a bile acid that is 5beta-cholan-24-oic acid bearing three alpha-hydroxy substituents at position 3, 7 and 12. It has a role as a human metabolite and a mouse metabolite. It is a bile acid, a C24-steroid, a 3alpha-hydroxy steroid, a 7alpha-hydroxy steroid, a 12alpha-hydroxy steroid and a trihydroxy-5beta-cholanic acid. It is a conjugate acid of a cholate. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | C[C@H](CCC(=O)O)[C@H]1CC[C@H]2[C@H]3[C@H](C[C@H](O)[C@@]21C)[C@@]1(C)CC[C@@H](O)C[C@H]1C[C@H]3O |
PDB | — |
CAS-ID | 81-25-4 |
RxCUI | — |
ChEMBL ID | CHEMBL205596 |
ChEBI ID | 16359 |
PubChem CID | 221493 |
DrugBank | DB02659 |
UNII ID | — |